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CBD vs The Hangover

CBD and Nausea

Hangovers can be debilitating. The feeling of Nausea is a common side-effect of a hangover. The feeling is miserable, and we usually spend the hours it takes to recover promising ourselves that we will NEVER allow ourselves to get that sick ever again. Usually that is not the case, and we repeatedly find ourselves in the grips of hangover hell.

When faced with crippling nausea, people typically use over-the-counter medicines such as Pepto Bismol, Dramamine, and Kaopectate. But what if you aren't willing or able to take any of those medicines?

Did you know that CBD has shown a lot of promise in preventing and easing nausea without the side effects induced by pharmaceutical anti-emetics? 

According to a 2014 review of scientific progress regarding CBD from the European Journal of Pharmacology :

“Cannabis has long been known to limit or prevent nausea and vomiting from a variety of causes. This has led to extensive investigations that have revealed an important role for cannabinoids and their receptors in the regulation of nausea and emesis (vomiting).”

Evidence from experiments shows that CBD can control nausea by acting on the serotonin receptors in the brain. Namely, CBD decreases the release of serotonin, which results in weaker stimulation on the vomiting controls in the brain. With the help of CBD, serotonin in our system becomes balanced and, thus, making it a great help to manage vertigo-induced nausea.

The anti-emetic properties of CBD are also linked to its influence on the CB1 cannabinoid receptors.

These receptors occur in the brainstem, where both THC and anandamide are used.

Studies show that increased production of anandamide, which is the CB1 agonist, relieves the feelings of nausea and reduces the urge to vomit. 

What Does the Research Say?

 

The anti-emetic effects of cannabinoids are one of the best-researched areas of their medical applications. Below I give you a list of three high-impact studies underscoring the potential of CBD to relieve and prevent nausea:

A 2002 study published in Neuroreport concluded:

“cannabidiol, a major non-psychoactive cannabinoid found in marijuana and its synthetic dimethylheptyl homolog interfere with nausea elicited by lithium chloride and with conditioned nausea elicited by a flavor paired with lithium chloride. These results suggest that cannabinoids without psychoactive side-effects may have therapeutic value in the treatment of chemotherapy-induced nausea.”

A 2011 research paper published in the British Journal of Pharmacology indicates that:

“The neural mechanisms of nausea are still not well understood. However, the anti-emetic effect of cannabinoids has been shown across a wide variety of animals that are capable of vomiting in response to a toxic challenge.”

In a 2016 report in Pharmacology, the researchers came with the following conclusion:

“Administered subthreshold combines doses of THC or CBDA to significantly suppress acute nausea, but individual doses of CBDA were maximally effective.”
 

Article Source: https://cfah.org/cbd-oil-for-nausea/